Casa Sant'Andrea is a former monastery that was renovated to become a characteristic Venetian Palace. It overlooks the canal of Santa Chiara, close to Piazzale Roma.
You can walk to Santa Lucia Train Station, and take advantage of the nearby water-bus stop to visit the rest of Venice.
The rooms at the Sant'Andrea are functional and comfortable. Some rooms are en suite and some share a bathroom. A shared lounge area with a TV is available.